Access Denied
IMPORTANT! If you’re a store owner, please make sure you have Customer accounts enabled in your Store Admin, as you have customer based locks set up with EasyLockdown app. Enable Customer Accounts
ENGINEERED TO MAXIMIZE THE DELIVERABLE BIOLOGICAL PAYLOAD
PLATELET-RICH PLASMA CONCENTRATE (PRPC), ENGINEERED FOR POINT-OF-CARE
The principal contribution of ExoCube is not activation alone, but concentration of the released biological payload into a substantially reduced plasma volume.
Independent Laboratory Evaluation
91%
Plated
Recovery
~3x
Growth Factor
Enrichment
5.8x
A2M
Enrichment
11
Biomarkers
Measured
WHY EXOCUBE
GENERATION III AUTOLOGOUS BIOLOGICS
AN AUTOLOGOUS APPROACH TO PRPC PREPARATION
A new approach to autologous biologics. ExoCube™ transforms autologous blood into Platelet Rich Plasma Concentrate (PRPC) through a controlled four step process of plasma separation, activation, filtration, and concentration. Designed as a standardized, closed single use system, it prepares a concentrated biological payload enriched with measurable growth factors and plasma derived regulatory proteins while supporting consistent and reproducible preparation.
'Therapeutic value depends on the final deliverable biological payload, not platelet count alone.'
Rather than stopping after platelet collection, ExoCube™ performs three critical processing steps. This workflow is designed to concentrate the biological mediators released from platelets into a smaller final volume. No additional platelets are created—the mediators released from the recovered platelets are concentrated to prepare a more biologically enriched final product.
The Fundamental Question
Is More Platelets Always Better?
For years, autologous biologic procedures have focused on a single question: “How many platelets are being delivered?” But platelets themselves are not the therapeutic endpoint. Platelets serve as biological reservoirs that store and release signaling molecules responsible for tissue communication. Ultimately, the biological response depends on the concentration and availability of these mediators—not simply on platelet count.
Traditional Thinking
- How many billion platelets?
- Platelet count is considered the primary measure of product quality.
Generation III Thinking
- Platelets are the source. The biological mediators they release are the true biological payload.
Three Generations. One Evolution.
Beyond platelet recovery
A new generation of autologous biologics.
Generation I- Traditional PRP
Platelet Concentration
Primary focus Platelet recovery Variable platelet concentrations Variable plasma composition Designed to prepare platelet-rich plasma using centrifugation-based workflows. Discussion focused on “How many billion platelets?”
Generation II — PRF / CGF
Platelet Concentration
Primary Focus: Platelet-derived preparations.
Expanded focus
- Fibrin matrix formation
- Growth factor retention
- Structural scaffold formation
Introduced fibrin-based processing approaches that altered growth factor release characteristics.
- Extended mediator release
Still primarily centered around platelet-derived preparations.
Generation III— EXOCUBE
Moves beyond platelet recovery by integrating
ExoCube™ integrates three sequential processing steps into a standardized workflow:
- Platelet Activation
- Filtration
- Concentration
The resulting processed plasma demonstrated enrichment of multiple platelet-derived growth factors together with plasma-derived regulatory proteins in independent laboratory evaluation.
WHY GENERATION III?
Earlier technologies primarily focused on platelet collection.
Primary Focus: A concentrated biological payload.
ExoCube™ expands the workflow by incorporating:
✔ Platelet activation
✔ Filtration
✔ Plasma concentration
to prepare a concentrated platelet-associated plasma fraction with a broad measurable biological profile.
Invalid password
Enter